Thiamax contains a highly-bioavailable derivative of thiamine (vitamin B1) called TTFD – thiamine tetrahydrofurfuryl disulfide. This form has been widely researched in Japan for its therapeutic potential in addressing thiamine insufficiency.
Unlike other forms of thiamine supplementation, TTFD’s molecular structure allows it to pass through intestinal and cellular membranes without the requirement for a transport system. Once inside the cell, it can be activated and used as a cofactor in important biochemical processes.
TTFD also has a demonstrated capacity to penetrate the blood brain barrier and increase thiamine levels in the brain and central nervous system, where it may be used to support optimal cognition and maintain autonomic nervous system function.
Due to its superior bioavailability, TTFD can be taken in much lower doses than what is considered the “therapeutic dose” of other forms such as thiamine salts. Thiamax also contains a small amount of magnesium (as magnesium taurate), which is a mineral that is important for supporting how cells can utilize thiamine.
How to use
- Take one capsule per day with or without food.
- Avoid coffee/tea consumption either one hour before or two hours after taking thiamax.
- Avoid taking this product in the afternoon/evening, as it may interfere with sleep.
- Should be taken alongside 200-400mg of magnesium & a high quality B-complex
For first time users who consider themselves sensitive to supplements:
- Start with half or quarter of a capsule per day by emptying half of the capsule contents into a small glass of water.
- Increase the dose every three or four days until you reach one full capsule.
- In some individuals, supplementation with Thiamax can induce a temporary worsening of certain symptoms such as fatigue, brain-fog, and digestive bloating or gas. This usually lasts for around one week, and is referred to as the “paradoxical reaction”.
Frequently Asked Questions
For people who have never taken thiamine TTFD before, it is best to start with half or quarter of a capsule. This can be done simply by opening a capsule and emptying a portion of the contents into a cold drink or cold food.
Thiamax is best taken in the morning time or early afternoon. If taken in the evening, it may disrupt sleep. Thiamax should be taken at least 1 hour before, or two hours after consuming coffee or green/black tea.
Thiamax can be taken with or without food. The absorption is similar either way.
Initially some people can experience a “paradoxical reaction”with thiamine supplementation. This might include a temporary period of increased fatigue, brain-fog, and poor concentration. This reaction usually subsides within a few weeks.
Although some people can benefit from taking multiple capsules, it is advised that someone does not go higher than 3-4 capsules without the guidance of a healthcare practitioner.
Generally, it is advised that people supplement with 200-400mg of magnesium (in supplemental form) on the same day as supplementing Thiamax, along with a good-quality B vitamin complex. However, you should consult with your healthcare provider for specific advice on this topic.