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Fibromyalgia is a condition known for widespread pain and fatigue, but what’s going on inside the body to cause these symptoms? Research points to a problem with how cells produce energy. Each cell has its own tiny power plant called the mitochondria, which converts food into energy using oxygen and nutrients. When this process breaks down, it’s called mitochondrial dysfunction, and it’s a key player in fibromyalgia.
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Fibromyalgia (FMS) is a complex chronic condition characterized by allodynia, pain, stiffness, parasthesias, and tenderness of the muscles, skin, and soft tissues. It also may feature HPA-axis dysregulation, circadian abnormalities, fatigue and muscle weakness, depression, and insomnia. Biochemical abnormalities include elevated markers of system oxidative stress, inflammation, and mitochondrial dysfunction. Many in the FMS community have achieved great successes using high doses of thiamine.
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