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Leaky Gut Syndrome, though often overlooked, is a common feature of chronic disease of many kinds. The exact phrase “leaky gut” is not usually found in the medical literature, though it is used to describe the process increased permeability of the intestinal barrier.
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In many people chronic upper constipation and GERD are misdiagnosed as bacterial overgrowth. Unfortunately, they are often non-responsive to antimicrobial treatments. Yet, sometimes the issues improve greatly with vitamin B1 repletion. In this case, the "SIBO" diagnosis is simply a symptom of an underlying systemic problem with energy metabolism.
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